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Index cases of melanoma were identified, by date of diagnosis, from histology records for inpatients and outpatients at the district's three hospitals for the year starting 1 April 1991. A small number of cases from general practitioners was also identified from the same source. Thirty six cases of primary cutaneous melanoma were identified. For the calendar year 1991 the Thames Cancer Registry recorded 19 cases of melanoma. The sampling frame for the local study accounted only for lesions verified histologically, but the cancer registry includes lesions not verified histologically. When this factor is taken into account the registry recorded only 16 cases of melanoma confirmed histologically, which is a substantial difference.
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