Editorials
A new agenda for AIDS research
Cautious optimism despite the growing need for answersAn air of cautious optimism characterised last month's meeting in London on advancing a new agenda for AIDS research. Laboratory, clinical, and social scientists from North America, South America, and Europe gathered at the Ciba Foundation to take stock of research performed so far and to set an agenda for the future.
The optimism stemmed largely from progress in basic scientific research. Several speakers confirmed our now intricate understanding of viral dynamics. David Ho from New York presented new data suggesting that the turnover of viruses and CD4 cells is even more rapid than previously estimated. The life cycle of a virus--from the time it enters one cell to the time it enters the next--seems to be 1.2 days, with 10 billion new virions being made each day. This clearly presents an enormous burden for the immune system; but data from the
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