BMJ 2001;323:293-294 ( 11 August )

Editorials

Management of nodular thyroid disease

The challenge remains identifying which palpable nodules are malignant

The first 150 words of the full text of this article appear below.

Thyroid nodules are found in 5% of middle aged women and are commoner in women than in men. A nodule raises concerns about malignant disease, but thyroid cancer is rare, accounting for about 1000 new cases in England and Wales each year. The main aim of management is to identify the small proportion of patients with thyroid cancer who require treatment and avoid unnecessary testing and treatment for the majority.

Nodules are more likely to be malignant in men, particularly men aged over 70.1 A history of neck irradiation, rapid tumour growth, or a family history of thyroid cancer increases risk. Physical signs associated with increased risk include firm, non-tender nodules, local lymphadenopathy, and recurrent laryngeal nerve palsy in the absence of previous surgery. The incidence of cancer in those with clinical features strongly suggestive of malignancy is high,2 but most patients do not have these features.

Solitary nodules are more . . . [Full text of this article]


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Relevant Article

Nodular thyroid disease
G L Sayer and M Keston Jones
BMJ 2001 323: 1184. [Extract] [Full Text]

This article has been cited by other articles:

  • Erbil, Y., Barbaros, U., Salmaslioglu, A., Mete, O., Issever, H., Ozarmagan, S., Yilmazbayhan, D., Tezelman, S. (2008). Effect of Thyroid Gland Volume in Preoperative Detection of Suspected Malignant Thyroid Nodules in a Multinodular Goiter. Arch Surg 143: 558-563 [Abstract] [Full text]  
  • Michalopoulos, K., Gunasekaran, S., Moor, J. W, Bem, C. (2008). Dysphagia with a thyroid nodule: is there a primary aerodigestive malignancy?. JRSM 101: 144-145 [Abstract] [Full text]  
  • Owen, P J D, Lazarus, J H, Morse, R E (2003). Unusual complications of thyroid carcinoma. Postgrad. Med. J. 79: 55-56 [Abstract] [Full text]  
  • Sayer, G L, Jones, M K. (2001). Nodular thyroid disease. BMJ 323: 1184-1184 [Full text]  

Rapid Responses:

Read all Rapid Responses

Are thyroid function tests helpful in the diagnosis of nodular thyroid disease?
G L Sayer
bmj.com, 13 Aug 2001 [Full text]
Management of nodular thyroid disease. Is there a role for ultrasound guided FNAC?
Ricard Simo
bmj.com, 29 Aug 2001 [Full text]
Measurement of hTERT in the Management of Thyroid Nodules
K L Kirkpatrick, et al.
bmj.com, 2 Sep 2001 [Full text]
Author's reply
M Keston Jones
bmj.com, 13 Sep 2001 [Full text]



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