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Published 31 July 2008, doi:10.1136/bmj.a755
Cite this as: BMJ 2008;337:a755
Can reduce weight and improve long term survival, but the risks must also be considered
| The first 150 words of the full text of this article appear below. |
Severe obesity (body mass index
40) has been linked to shorter survival, poorer mental and physical health, and substantial healthcare costs. Bariatric procedures, such as gastric bypass and gastric banding, dramatically reduce weight through gastric restriction, malabsorption, changes in neuroendocrine signalling, or a combination of these mechanisms.
One criticism of bariatric surgery has been the paucity of studies comparing its outcomes against non-surgical treatment. However, two recent controlled non-randomised studies found that bariatric surgery improved long term survival.1 2 The first was a prospective study that matched 2010 patients who had undergone bariatric surgery with 2037 non-surgical controls.1 After a mean of 10.9 years (with 99.9% follow-up), 6.3% of controls had died compared with 5.0% of surgical patients (hazard ratio 0.76, 95% confidence interval 0.59 to 0.99, number needed to treat 77). The second was a retrospective study of 9949 patients who had gastric bypass surgery and 9628 matched non-surgical controls.2
David Arterburn, assistant investigator
1 Group Health Center for Health Studies, Seattle, WA 98101, USA
arterburn.d@ghc.org
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