Framingham model for risk of heart disease fits a British population well

A person's absolute risk of developing heart disease can be derived from risk tables that are derived from the Framingham model, which was based on a US population. To see if this model accurately predicts the risk of coronary heart disease among a UK population Ramachandran et al studied 2779 people recruited in north east England in 1972-4 and followed up 20 years later (p 676). Predicted and observed numbers of coronary events agreed well at annual risks above 1.5%, but at lower risks the model underestimated the risk.


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Relevant Article

Using the Framingham model to predict heart disease in the United Kingdom: retrospective study
S Ramachandran, J M French, M P J Vanderpump, P Croft, and R H Neary
BMJ 2000 320: 676-677. [Extract] [Full Text] [PDF]




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