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In the next five to 15 years new vaccines and new technology for
delivering them will fundamentally change how clinicians prevent and
treat disease, with substantial impact on public health. Poland and
colleagues (p 1315) describe how advances in current vaccines, such as
conjugated pneumococcal and nasal spray vaccines, will provide an
efficient way to produce longlasting protective immunity. The future
holds the development of new vaccines against non-infectious diseases
such as cancer, diabetes, and even nicotine dependence. However,
concerns about vaccine safety and a rise in anti-vaccine sentiment are
currently adversely affecting the use and development of new vaccines.