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Children with autism are no more likely than children without
autism to have had a defined gastrointestinal disorder at any time
before autism is diagnosed. In a case-control study by Black and
colleagues (p 419), 96 cases of autism were identified from the UK
general practice research database between 1988 and 1999. Each was
matched with up to five controls. A history of chronic gastrointestinal
inflammation, coeliac disease, food intolerance, or recurrent
gastrointestinal symptoms was not more common in children with autism
than in those without autism.