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Bacterial vaginosis is not a strong risk factor for miscarriage
before 16 weeks' gestation, but it may be associated with miscarriage
in the second trimester. Oakeshott and colleagues (p 1334) conducted a
prospective cohort study of 1216 pregnant women attending general
practices and family planning clinics. Although treatment of
asymptomatic bacterial vaginosis is unlikely to prevent miscarriage in
the first trimester, initiatives to prevent miscarriage in the second
trimester and preterm birth should consider screening and treatment
before 13 weeks' gestation. Non-invasive screening for bacterial
vaginosis by using self-administered vaginal swaps is feasible in
community based, healthy pregnant women.