BMJ  2004;329 (10 July), doi:10.1136/bmj.329.7457.0-b

Narrowed retinal arterioles predict development of hypertension

People with narrowed retinal vessels are more likely to develop hypertension. Following up 2451 people who had normal blood pressure and had had the diameter of retinal arterioles and venules measured at baseline, Wong and colleagues (p 79) found that, at 10 years, people with the smallest vessel ratio had three times the risk of developing hypertension than did those with the highest ratio. Small vessel disease may be linked with the development of hypertension, say the authors, and it may be a target for antihypertensive treatment.

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Prospective cohort study of retinal vessel diameters and risk of hypertension

Tien Yin Wong, Anoop Shankar, Ronald Klein, Barbara E K Klein, and Larry D Hubbard
BMJ 2004 329: 79. [Abstract] [Full Text] [PDF]