BMJ  2005;331 (2 July), doi:10.1136/bmj.331.7507.0

Epilepsy and schizophrenia may share common causes

Patients with epilepsy are about two and a half times more likely to have schizophrenia and almost three times more likely to have schizophrenia-like psychosis than people without epilepsy. In a population based cohort study that included 2.27 million people from Danish longitudinal registers, Qin and colleagues (p 23) also found that family histories of epilepsy or psychosis were significant risk factors for schizophrenia or schizophrenia-like psychosis and the effect did not differ by type of epilepsy. Also, the effect did not show significant differences between men and women.

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Relevant Article

Risk for schizophrenia and schizophrenia-like psychosis among patients with epilepsy: population based cohort study

Ping Qin, Huilan Xu, Thomas Munk Laursen, Mogens Vestergaard, and Preben Bo Mortensen
BMJ 2005 331: 23. [Abstract] [Full Text] [PDF]