BMJ  2005;331 (8 October), doi:10.1136/bmj.331.7520.0-f

Adequate dietary folate may reduce alcohol related breast cancer

Adequate folate supplementation may protect against alcohol related increased risk of breast cancer. In a prospective cohort study of more than 17 000 Australian women for 10 years, Baglietto and colleagues (p 807) found that women who regularly consumed more than 40 g (5 units) a day of alcohol had a 40% greater risk of invasive breast cancer than lifetime abstainers. A daily folate intake of 400 µg in this drinking group, however, was associated with a significant reduction in risk compared with a daily intake of 200 µg (hazard ratios of 0.77 and 2.00 respectively).

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Relevant Article

Does dietary folate intake modify effect of alcohol consumption on breast cancer risk? Prospective cohort study

Laura Baglietto, Dallas R English, Dorota M Gertig, John L Hopper, and Graham G Giles
BMJ 2005 331: 807. [Abstract] [Full Text] [PDF]