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BMJ 2005;331 (15 October), doi:10.1136/bmj.331.7521.0-d
Left handed women have more than twice the risk of developing breast cancer before reaching the menopause than right handed women. In a population based prospective case-cohort study of more than 12 000 women who were followed up for 16 years, Ramadhani and colleagues (p 882) also found that the risk of postmenopausal breast cancer was similar for left handed and non-left handed women. A plausible pathophysiological explanation is the existence of common intrauterine hormonal influences that determine both cerebral lateralisation and risk of breast cancer.
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