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BMJ 2006;332 (14 January), doi:10.1136/bmj.332.7533.0-a
Using adjunctive testing for human papillomavirus (HPV) to triage women who have borderline and mildly dyskaryotic cervical smears costs more than repeat cytology, but it saves slightly more lives and could be cost effective in the long term. Legood and colleagues (p 79) modelled screening data of more than 10 000 women aged 25-64 from three centres participating in NHS pilot studies (p 83) which found that HPV triage leads to reduced rates of repeat smears but increased referrals to colposcopy.
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