BMJ  2006;332 (28 January), doi:10.1136/bmj.332.7535.0

H pylori screening and eradication cuts dyspepsia—but at a cost

Community based screening and eradication of Helicobacter pylori offers long term relief from dyspepsia but does not save money. Lane and colleagues (p 199) randomised more than 1500 patients who screened positive for H pylori to eradication therapy or placebo. Over the next two years, quality of life was the same in both groups but 35% fewer participants in the eradication group consulted for dyspepsia than in the placebo group. Even so, overall costs to the NHS were higher in the eradication group.

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Relevant Article

Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial

J Athene Lane, Liam J Murray, Sian Noble, Matthias Egger, Ian M Harvey, Jenny L Donovan, Prakash Nair, and Richard F Harvey
BMJ 2006 332: 199-204. [Abstract] [Full Text] [PDF]