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BMJ 2006;332 (18 February), doi:10.1136/bmj.332.7538.0-d
Treatment for Dupuytren's contracture is often unnecessary, but regular follow-up is needed to detect early joint contracture, say Townley and colleagues on page 397. This clinical review of Dupuytren's disease looks at presentation, epidemiology, associations, and pathophysiology of the disabling condition and discusses referral and surgical correction when contracture develops. Although timely surgery can prevent permanent loss of function, it cannot prevent recurrence. Some hopes might be pinned on recent research on medical treatment optionsfor instance, injection of collagenase, which has shown early clinical promise for mild disease.
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