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BMJ 2006;332 (18 March), doi:10.1136/bmj.332.7542.0-a
When children with cystic fibrosis and suboptimal nutrition receive regular dietary advice, providing oral protein energy supplements confers no additional improvement in nutritional status. In a multicentre randomised trial of more than 100 moderately malnourished children aged 2-15 years with cystic fibrosis, Poustie and colleagues (p 632) found no difference in mean change in body mass index centile or other nutritional and spirometric outcomes from baseline to 12 months between the children who received dietary advice plus dietary supplements and those who received only advice.
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