BMJ  2006;332 (25 March), doi:10.1136/bmj.332.7543.0-b

Breast cancer screening yields 10% over-diagnosis

Mammographic screening of women aged 55 years or older leads to a 10% over-diagnosis of breast cancer (detection of cases that would otherwise never have come to clinical attention). Zackrisson and colleagues (p 689) undertook a follow-up study of the participants from a Swedish trial that had randomised more than 42 000 women aged 45-69 to mammographic screening or not (control). Fifteen years after the end of that trial, over-diagnosis was 10% in the women randomised to screening at age 55-69 compared with the unscreened controls.

Credit: ALIX/PHANIE/REX

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Rate of over-diagnosis of breast cancer 15 years after end of Malmö mammographic screening trial: follow-up study

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