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BMJ 2006;332 (15 April), doi:10.1136/bmj.332.7546.0-a
The presence of the metabolic syndrome helps to predict risk for total and cardiovascular mortality above and beyond the usual cardiovascular disease risk factors, report Sundström and colleagues (p 878), who studied 2300 middle aged men for up to 32 years. When the metabolic syndrome was added to models of established cardiovasular risk factors (smoking, diabetes, hypertension, and serum cholesterol), the risk for total and cardiovascular mortality increased by 40-60%. In a commentary, however, Farmer (p 882) points out that research on the metabolic syndrome has so far yielded mixed results.
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