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BMJ 2006;333 (19 August), doi:10.1136/bmj.333.7564.0-d
Because of its chronic, incurable nature, psoriasis is associated with substantial morbidity. Anxiety and depression affect up to 25% of patients, and are often missed. Patients with severe disease also have an increased risk for cardiovascular disease. The clinical review by Smith and Barker (p 380) revisits the causes and diagnosis of this inflammatory skin disease, describes its significant clinical effects and comorbidities, outlines the treatment options (from topical therapy to recently licensed biological treatments), and discusses how treatment should be provided.
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