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BMJ 2006;333 (14 October), doi:10.1136/bmj.333.7572.0
Calcium supplementation has little effect on bone mineral density in healthy children say Winzenberg and colleagues (p 775). Their meta-analysis of 19 randomised controlled trials, which involved more than 2800 healthy children aged 3-18 years, found that calcium supplements had no effect at the hip or lumbar spine. Upper limb bone density improved to a small degree. As they found only weak evidence that this effect persists, calcium supplements are unlikely to decrease fracture risk to a degree of major public health importance.
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