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BMJ 2006;333 (9 December), doi:10.1136/bmj.333.7580.0-d
Effective treatment of hyperglycaemia and strict glycaemic control are key to reducing microvascular complications in patients with type 2 diabetes. In a clinical review (doi: 10.1136/bmj.39022.462546.80), Heine and colleagues say that achieving this goal usually involves complex treatment with combinations of glucose lowering agents. Because the natural course of type 2 diabetes is characterised by a gradual decline in
cell function, the usual stepped approach to management often results in recurrent hyperglycaemia. The authors discuss effective interventions that reduce treatment failure and improve long term outcomes.
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