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BMJ 2006;333 (16 December), doi:10.1136/bmj.333.7581.0-c
Considerable advances have been made in identifying people at risk of fractures because of osteoporosis and in treatments designed to reduce fractures, say Poole and Compston (10.1136/bmj.39050.597350.47) in their clinical review of the management of osteoporosis. They discuss the genetic, nutritional, hormonal, and physical factors that influence peak bone mass, which is attained in the third decade and determines bone mineral density in later life. Avoidable clinical risk factors for fragility fractures include smoking, high alcohol consumption, low body mass index, and falls.
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