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Published 4 March 2009, doi:10.1136/bmj.b783
Cite this as: BMJ 2009;338:b783
The answer to this question, and more questions on this topic, are available from www.onexamination.com/endgames until midnight on Wednesday.
This weeks quiz is on stroke and is taken from the MRCP and MRCPI examinations.
A 35 year old woman was admitted to casualty after developing restlessness, hallucinations, and acute confusion. The symptoms came on within minutes of her having taken sumatriptan for migraine.
On admission she was vomiting and sweating profusely and seemed to be confused, with a Glasgow coma score of 14/15. Her blood pressure was 162/90 mm Hg, her pulse was 102 beats per minute and regular, and her temperature was 38.9°C. Heart sounds were normal, and her chest was clear on auscultation. A cranial nerve examination including fundoscopy was normal. Examination of the peripheral nervous system revealed normal tone, with four beats of ankle clonus bilaterally. Her reflexes were globally brisk, although power, sensation, and coordination were all normal.
The patient was taking fluoxetine for depression and sumatriptan for occasional migraines. She was a non-smoker and drank 10 units of alcohol a week.
Investigations showed: sodium 135 mmol/l (normal 137-144), potassium 3.9 mmol/l (3.5-4.9), urea 8.9 mmol/l (2.5-7.5), creatinine 130 mol/l (60-110), haemoglobin 10.2 g/dl (11.5-16.5), white cell count 12x109/l (4-11x109), platelets 100x109/l (150-400x109), prothrombin time 20.2 s (11.5-15.5), activated partial thromboplastin time 50 s (30-40), fibrinogen 7.8 g/l (1.8-5.4).
Which one of these potential therapeutic options should the patient not be given?
Cite this as: BMJ 2009;338:b783
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